A Sequence of Experiments for Translational Therapeutic Investigations

Chap T. Le, PhD
Distinguished Teaching Professor of Biostatistics
University of Minnesota

Wednesday, December 2, 2009
3:30pm
Weaver-Densford Hall 2-120
Minneapolis Campus

Abstract:

Details are given and proposed for a sequence of experiments used in translational therapeutic investigations:
(1) The Dose-ranging experiment; followed by (2) The trial for efficacy and (3) The trial for drug combinations
and testing for synergistic effects. Serious questions will be raised concerning a very popular method, the
"Combination Index" by Chou and Talalay.

A social tea will be held at 3:00 P.M. in A434 Mayo. All are Welcome.
For more details contact 612-624-4655 or see http://www.biostat.umn.edu/seminar_academic.html