Title: Intermediate Bayesian Data Analysis Using WinBUGS and BRugs Instructor: Brad Carlin, University of Minnesota Abstract: Most statisticians and health policy researchers have been exposed to Bayesian methods, and have some idea about the hierarchical modeling and other settings in which they offer substantial benefits. But actually obtaining these benefits remains out of reach for many, due to a lack of experience with modern Bayesian software in the analysis of real data. In this workshop, we will offer a hands-on opportunity to explore the use of WinBUGS, the leading Bayesian software package, in a variety of important models, with special attention paid to clinical trial design and analysis, and to joint models for longitudinal measurements and survival data. Basic elements such as model building, MCMC convergence diagnosis and acceleration, and posterior plotting and summarization will be mentioned, as well as (time permitting) important data-analytic procedures such as residual analysis, model adequacy (through Bayesian p-values and CPO statistics), variable selection, and model choice (through posterior probabilities and DIC statistics). In addition to WinBUGS, we will also provide a brief introduction to BRugs, the new version of BUGS available directly within the popular R package, which enables simultaneous use of the features of both languages. Students should bring their own laptop computers to the session, and to have the latest versions of WinBUGS and R already installed on these computers. Both of these programs are freely available from http://www.mrc-bsu.cam.ac.uk/bugs/winbugs/contents.shtml and http://www.r-project.org/ respectively. The presentation will assume familiarity with basic Bayesian methods and MCMC algorithms, at the level of, say, Chapters 2 and 5 of Carlin and Louis (2000) or Chapters 2, 3, 5 and 11 of Gelman et al. (2004). The workshop's goal is to make these methods come alive in the software through real data examples that the students try for themselves during the presentation. All necessary WinBUGS and BRugs code will be made available on the web, with the joint modeling material located at http://www.biostat.umn.edu/~brad/software.html