Data sets and associated software programs for Bayesian Adaptive Methods for Clinical Trials (ISBN: TBA), by S.M. Berry, B.P. Carlin, J.J. Lee, and P. Muller, Boca Raton, FL: Chapman and Hall/CRC Press, 2010.

Here are electronic versions of the many of the the data sets and computer programs, and their page number(s) in Chapter 3 of the book -- help yourself!

phaseIsim.zip, the zip file that contains the phaseIsim.R program for the continual reassessment methods (CRM) and related supporting files (p. 100)
phaseIsim_R.txt, Brad's version of Jack's phaseIsim.R program; bottom of file has function calls that create BCLM Table 3.2, Scenario 1 (p. 100)
CRMdemo.zip (p. 101)
CRMexplore.zip (p. 101)
CRMinteractive.zip (p. 101)

EWOC.txt, WinBUGS code to implement the escalation with overdose control (EWOC) method in Example 3.4 (pp. 104-105)

titecrm.R, a basic R implementation of the TITE-CRM method (p. 106)

324.R, a basic R implementation of the Ji, Li, and Bekele (2007) method for toxicity intervals (p. 110)

354.R, a basic R implementation of the 2-agent dose escalation method of Thall et al (2003) (p. 132)


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