### Data sets and associated software programs for
*Bayesian Adaptive Methods for Clinical Trials*
(ISBN: TBA),
by S.M. Berry, B.P. Carlin, J.J. Lee, and P. Muller,
Boca Raton, FL: Chapman and Hall/CRC Press, 2010.

Here are electronic versions of the many of the the data sets
and computer programs, and their page number(s) in
Chapter 4
of the book -- help yourself!
Phase II PP Design,
a standalone desktop program to implement the Phase II predictive
probability designs of the sort illustrated in Example 4.2 (p. 149)

MultcLean,
the "lean" version of the **Multc** clinical trial software
that enables stopping for futility, efficacy, or toxicity with
binary data (p. 152)

431.R,
a simple R implementation of this same basic approach, e.g.,
Thall Simon and Estey (1995) (p. 152)

Adaptive Randomization (AR),
the MD Anderson software package used to implement Algorithm 4.3 in
Example 4.4 (p. 156)

35.R,
a basic R implementation of the
optimal biologic dosing method (Algorithm 4.4) using the
FFBS method (Algorithm 4.5) in Example 4.5 (pp. 164-167)

443.R,
a basic R implementation of the Huang et al (2009) method
adaptive allocation with survival response, illustrated in
Example 4.7 (p. 171); see also
this
helpful debugging note from Dr. John Reynolds of Monash University.

seqdesphII,
a software package written by David Rossell for implementing the
decision-theoretic screening design of Algorithm 4.9; look under "2006
papers" (p. 180)

Back to
the book's data page

Back to
Brad Carlin's home page