# Revisions: # June 18, 2002: Explore using Gamma(1,1) prior for lambda_k. # Nov. 9, 2001: standardize etas so that lung cancer doesn't drive all the maps. # Nov. 12, 2001: incorporate both prevention & outcome into one model (so don't have to change inits & rerun) # Also, add code to look at ranks. # Dec. 6, 2001: reverse incidence & mortality weights for crc in the prevention-emphasis scheme # if you want hard-coded isigsq, # comment out the lines where bcisigsq[1-4] are drawn from Gamma distributions. # uncomment the lines where they are set. # remove initialization of bcisigsq (etc) from the inits lists (for the 3 chains) # REMEMBER: I never used hard-coded values for isigsq for crc or lc; just for bc. # if you want isigsq to be drawn from a prior distribution, # uncomment the lines where bcisigsq[1-4] are drawn from Gamma distributions. # comment out the lines where they are set. # be sure to set isiga and isigb in the data section -- they are the parameters for the Gamma distribution. # Include the following: (In each case, discard first 5k samples, save summary of next 5k samples) # Seed: 2236 Runs for random sigma, random lambda, standard units: # bc: all rates per 100k, percentages in [0,100] -- graphs, standardized and not stdized. # (i.e. in the various arrays, the first values are: # bcincidencerate(128.2),bcmortalityrate(18.3),bcstagingpct(31.82),bcmamnotpct(21.74) # Gamma(.01,.01) priors on each of the sigma^2's and lambda's ### -- so for this setup, want to record these variables ######## pbcetaun -- bcp_un1_jun18.txt (row 2 of FIg 2) ######## pbcetast -- bcp_st1_jun18.txt (row 2 of Fig 2) (and in Fig 3) ######## obcetast -- bco_st1_jun18.txt (Fig 5) ######## pcrcetast -- crcp_st1_jun18.txt, (Fig 3) ######## ocrcetast -- crco_st1_jun18.txt, (Fig 5) ######## plcetast -- lcp_st1_jun18.txt, (Fig 3) ######## olcetast -- lco_st1_jun18.txt, (Fig 5) ######## petafinal -- allp_jun18.txt (Fig 3) ######## oetafinal -- allo_jun18.txt (Fig 5) # Seed: 93845. same units as above; Gamma(4,0.2) priors on lambdas; #### pbcetast --> bcp_st4_jun19.txt --> bcp_gam42_bw.ps #### plcetast --> lcp_st4_jun19.txt --> lcp_gam42_bw.ps #### pcrcetast --> crcp_st4_jun19.txt --> crcp_gam42_bw.ps #### petafinal --> allp_st4_jun19.txt --> allp_gam42_bw.ps ## Seed: 321233 Random sigma, random lambda, emphasize incidence: (Row 3 of Figure 2) # bc: incidence per 1,000k, mortality/1000, percents in [0,1] -- graphs, stdized & not stdized. # (i.e. earlier incidence rate * 10 and mortality rate / 100 and screen,staging divided by 100) # bcincidencerate(1282),bcmortalityrate(.183),bcstagingpct(.3182),bcmamnotpct(.2174) # Gamma(.01,.01) priors on each of the sigma^2's and lambda's ### -- so for this setup, want to record the variables: ######## pbcetast -- bcp_st2_jun18.txt (3rd row of Fig 2) ######## pbcetaun -- bcp_un2_jun18.txt (3rd row of Fig 2) # Seed: 502050 Sigma fixed, lambda random, standard units for input vars (Figure 2, top row) # i.e. staging/screening rates/100k, %'s in [0,100]. Gamma(.01,.01) priors for lambda, isigma^2. ### So for this setup, record the following variables: ######## pbcetaun -- bcp_un3_jun18.txt (Fig 2, left column) ######## pbcetast -- bcp_st3_jun18.txt (Fig 2, right column) # Generate 12 prevention maps, for bc only: (components of Figure 2) # bcp_un1_rwb.ps & bcp_un1_bw.ps ( sigma fixed, red/white/blue or black/white )(unstandardized) # bcp_st1_rwb.ps & bcp_st1_bw.ps ( sigma fixed, red/white/blue or black/white )(standardized) # bcp_un2_rwb.ps & bcp_un2_bw.ps ( sigma random, std wts, red/white/blue or black/white )(unstandardized) # bcp_st2_rwb.ps & bcp_st2_bw.ps ( sigma random, std wts, red/white/blue or black/white )(standardized) # bcp_un3_rwb.ps & bcp_un3_bw.ps ( sigma random, empasize incid., red/white/blue or black/white )(unstandardized) # bcp_st3_rwb.ps & bcp_st3_bw.ps ( sigma random, empasize incid., red/white/blue or black/white )(standardized) # Generate 4 prevention maps, one for each cancer type, plus combine the three. # bcp_rwb.ps, lcp_rwb.ps, crcp_rwb.ps, allp_rwb.ps, sim. for bw instead of rwb. # Generate 4 outcome maps, one for each cancer type, plus combine the three. # bco_rwb.ps, lco_rwb.ps, crco_rwb.ps, allo_rwb.ps, sim. for bw instead of rwb. # variable and file naming conventions: # "bc" for Breast Cancer, "lc" for Lung Cancer, "crc" for Colorectal Cancer. # "p" stands for prevention weighting, "o" for outcome weighting. # "st" if standardizing gibbs samples, "un" if not standardizing. # e.g. lcp_something means Lung Cancer, using Prevention Weighting. model { isigaa <- isiga isigbb <- isigb ############################### ##### BREAST CANCER VARS ##### ############################### ########## Breast cancer mortality ############## bctheta1[1:regions] ~ car.normal(adj[],weights[],num[],bclambda[1]) #bcisigsq[1] <- 0.15 bcisigsq[1] ~ dgamma(isiga,isigb) bclambda[1] ~ dgamma(ilama,ilamb) bcsig[1] <- 1/sqrt(bcisigsq[1]) bcmu[1] ~ dflat() ############ Breast cancer incidence ############ bctheta2[1:regions] ~ car.normal(adj[],weights[],num[],bclambda[2]) # bcisigsq[2] <- .01 bcisigsq[2] ~ dgamma(isiga,isigb) bclambda[2] ~ dgamma(ilama,ilamb) bcsig[2] <- 1/sqrt(bcisigsq[2]) bcmu[2] ~ dflat() ############# Breast cancer staging ############ bctheta3[1:regions] ~ car.normal(adj[],weights[],num[],bclambda[3]) #bcisigsq[3] <- 0.002 bcisigsq[3] ~ dgamma(isiga,isigb) bclambda[3] ~ dgamma(ilama,ilamb) bcsig[3] <- 1/sqrt(bcisigsq[3]) bcmu[3] ~ dflat() ############## Breast cancer screening ########## bctheta4[1:regions] ~ car.normal(adj[],weights[],num[],bclambda[4]) #bcisigsq[4] <- .003 bcisigsq[4] ~ dgamma(isiga,isigb) bclambda[4] ~ dgamma(ilama,ilamb) bcsig[4] <- 1/sqrt(bcisigsq[4]) bcmu[4] ~ dflat() ########## Breast cancer ############## for (i in 1:regions) { bcprecis[1,i] <- bcisigsq[1]*bcdeaths[i]/bcmortalityrate[i] bcmeen[1,i] <- bcmu[1] + bctheta1[i] bcmortalityrate[i] ~ dnorm( bcmeen[1,i], bcprecis[1,i]) bcprecis[2,i] <- bcisigsq[2]*bcincidence[i]/bcincidencerate[i] bcmeen[2,i] <- bcmu[2] + bctheta2[i] bcincidencerate[i] ~ dnorm( bcmeen[2,i], bcprecis[2,i]) bcprecis[3,i] <- bcisigsq[3]*bcstagingtot[i] bcmeen[3,i] <- bcmu[3] + bctheta3[i] bcstagingpct[i] ~ dnorm( bcmeen[3,i], bcprecis[3,i]) bcprecis[4,i] <- bcisigsq[4]*bcmamtot[i] bcmeen[4,i] <- bcmu[4] + bctheta4[i] bcmamnotpct[i] ~ dnorm( bcmeen[4,i], bcprecis[4,i]) } #### standardize the Gibbs sample for breast cancer: #### for (i in 1:4) { bcmeana[i] <- mean( bcmeen[i,] ) bcstda[i] <- sd( bcmeen[i,] ) } for (i in 1:regions) { for (k in 1:4) { bcmean[k,i] <- (bcmeen[k,i] - bcmeana[k]) /bcstda[k] } } ### Combine 4 measures for breast cancer, standardized and non-standardized: ### for (i in 1:regions) { # eta_un(standardized) and eta_st(andardized) pbcetaun[i] <- pbcmortwt*bcmeen[1,i] + pbcincwt*bcmeen[2,i] + pbcstagingwt*bcmeen[3,i] + pbcscreenwt*bcmeen[4,i] pbcetast[i] <- pbcmortwt*bcmean[1,i] + pbcincwt*bcmean[2,i] + pbcstagingwt*bcmean[3,i] + pbcscreenwt*bcmean[4,i] obcetaun[i] <- obcmortwt*bcmeen[1,i] + obcincwt*bcmeen[2,i] + obcstagingwt*bcmeen[3,i] + obcscreenwt*bcmeen[4,i] obcetast[i] <- obcmortwt*bcmean[1,i] + obcincwt*bcmean[2,i] + obcstagingwt*bcmean[3,i] + obcscreenwt*bcmean[4,i] } # bcStLouis <- rank( pbcetast[],69 ) # bcHenn <- rank( pbcetast[],27 ) # bcRock <- rank( pbcetast[],67) # bcKoochiching <- rank( pbcetast[],36 ) #### Code for tracking rank of various counties, for breast cancer: ### bcStLouis1 <- rank( bcmean[1,],69 ) bcHenn1 <- rank( bcmean[1,],27 ) bcRock1 <- rank( bcmean[1,],67) bcKoochiching1 <- rank( bcmean[1,],36 ) bcStLouis2 <- rank( bcmean[2,],69 ) bcHenn2 <- rank( bcmean[2,],27 ) bcRock2 <- rank( bcmean[2,],67) bcKoochiching2 <- rank( bcmean[2,],36 ) bcStLouis3 <- rank( bcmean[3,],69 ) bcHenn3 <- rank( bcmean[3,],27 ) bcRock3 <- rank( bcmean[3,],67) bcKoochiching3 <- rank( bcmean[3,],36 ) bcStLouis4 <- rank( bcmean[4,],69 ) bcHenn4 <- rank( bcmean[4,],27 ) bcRock4 <- rank( bcmean[4,],67) bcKoochiching4 <- rank( bcmean[4,],36 ) #################################### ##### COLORECTAL CANCER VARS ##### #################################### crctheta1[1:regions] ~ car.normal(adj[],weights[],num[],crclambda[1]) crclambda[1] ~ dgamma(ilama,ilamb) crcisigsq[1] ~ dgamma(isiga,isigb) crcsig[1] <- 1/sqrt(crcisigsq[1]) crcmu[1] ~ dflat() crctheta2[1:regions] ~ car.normal(adj[],weights[],num[],crclambda[2]) crclambda[2] ~ dgamma(ilama,ilamb) crcisigsq[2] ~ dgamma(isiga,isigb) crcsig[2] <- 1/sqrt(crcisigsq[2]) crcmu[2] ~ dflat() crctheta3[1:regions] ~ car.normal(adj[],weights[],num[],crclambda[3]) crclambda[3] ~ dgamma(ilama,ilamb) crcisigsq[3] ~ dgamma(isiga,isigb) crcsig[3] <- 1/sqrt(crcisigsq[3]) crcmu[3] ~ dflat() crctheta4[1:regions] ~ car.normal(adj[],weights[],num[],crclambda[4]) crclambda[4] ~ dgamma(ilama,ilamb) crcisigsq[4] ~ dgamma(isiga,isigb) crcsig[4] <- 1/sqrt(crcisigsq[4]) crcmu[4] ~ dflat() for (i in 1:regions) { crcprecis[1,i] <- crcisigsq[1]*crcdobs[i]/crcdrate[i] crcmeen[1,i] <- crcmu[1] + crctheta1[i] crcdrate[i] ~ dnorm( crcmeen[1,i], crcprecis[1,i]) crcprecis[2,i] <- crcisigsq[2]*crciobs[i]/crcirate[i] crcmeen[2,i] <- crcmu[2] + crctheta2[i] crcirate[i] ~ dnorm( crcmeen[2,i],crcprecis[2,i]) crcprecis[3,i] <- crcisigsq[3]*crcstagn[i] crcmeen[3,i] <- crcmu[3] + crctheta3[i] crcstagingpct[i] ~ dnorm( crcmeen[3,i], crcprecis[3,i]) crcprecis[4,i] <- crcisigsq[4]*crcscreen[i] crcmeen[4,i] <- crcmu[4] + crctheta4[i] crcnotscreenpct[i] ~ dnorm( crcmeen[4,i], crcprecis[4,i]) crceta[i] <- (crcmeen[1,i] + crcmeen[2,i])/4 + (crcmeen[3,i]+crcmeen[4,i])/4 } for (i in 1:4) { crcmeana[i] <- mean( crcmeen[i,] ) crcstda[i] <- sd( crcmeen[i,] ) } for (i in 1:regions) { for (k in 1:4) { crcmean[k,i] <- (crcmeen[k,i] - crcmeana[k]) /crcstda[k] } } for (i in 1:regions) { # eta_un(standardized) and eta_st(andardized) # pcrcetaun[i] <- pcrcmortwt*crcmeen[1,i] + pcrcincwt*crcmeen[2,i] + pcrcstagingwt*crcmeen[3,i] + pcrcscreenwt*crcmeen[4,i] pcrcetast[i] <- pcrcmortwt*crcmean[1,i] + pcrcincwt*crcmean[2,i] + pcrcstagingwt*crcmean[3,i] + pcrcscreenwt*crcmean[4,i] # ocrcetaun[i] <- ocrcmortwt*crcmeen[1,i] + ocrcincwt*crcmeen[2,i] + ocrcstagingwt*crcmeen[3,i] + ocrcscreenwt*crcmeen[4,i] ocrcetast[i] <- ocrcmortwt*crcmean[1,i] + ocrcincwt*crcmean[2,i] + ocrcstagingwt*crcmean[3,i] + ocrcscreenwt*crcmean[4,i] } # crcStLouis <- rank( pcrcetast[],69 ) # crcHenn <- rank( pcrcetast[],27 ) # crcRock <- rank( pcrcetast[],67) # crcKoochiching <- rank( pcrcetast[],36 ) crcStLouis1 <- rank( crcmean[1,],69 ) crcHenn1 <- rank( crcmean[1,],27 ) crcRock1 <- rank( crcmean[1,],67) crcKoochiching1 <- rank( crcmean[1,],36 ) crcStLouis2 <- rank( crcmean[2,],69 ) crcHenn2 <- rank( crcmean[2,],27 ) crcRock2 <- rank( crcmean[2,],67) crcKoochiching2 <- rank( crcmean[2,],36 ) crcStLouis3 <- rank( crcmean[3,],69 ) crcHenn3 <- rank( crcmean[3,],27 ) crcRock3 <- rank( crcmean[3,],67) crcKoochiching3 <- rank( crcmean[3,],36 ) crcStLouis4 <- rank( crcmean[4,],69 ) crcHenn4 <- rank( crcmean[4,],27 ) crcRock4 <- rank( crcmean[4,],67) crcKoochiching4 <- rank( crcmean[4,],36 ) #################################### ######### LUNG CANCER VARS ######## #################################### lctheta1[1:regions] ~ car.normal(adj[],weights[],num[],lclambda[1]) lclambda[1] ~ dgamma(ilama,ilamb) lcisigsq[1] ~ dgamma(isiga,isigb) lcsig[1] <- 1/sqrt(lcisigsq[1]) lcmu[1] ~ dflat() lctheta2[1:regions] ~ car.normal(adj[],weights[],num[],lclambda[2]) lclambda[2] ~ dgamma(ilama,ilamb) lcisigsq[2] ~ dgamma(isiga,isigb) lcsig[2] <- 1/sqrt(lcisigsq[2]) lcmu[2] ~ dflat() lctheta3[1:regions] ~ car.normal(adj[],weights[],num[],lclambda[3]) lclambda[3] ~ dgamma(ilama,ilamb) lcisigsq[3] ~ dgamma(isiga,isigb) lcsig[3] <- 1/sqrt(lcisigsq[3]) lcmu[3] ~ dflat() for (i in 1:regions) { lcprecis[1,i] <- lcisigsq[1]*lcdobs[i]/lcdrate[i] lcmeen[1,i] <- lcmu[1] + lctheta1[i] lcdrate[i] ~ dnorm( lcmeen[1,i], lcprecis[1,i]) lcprecis[2,i] <- lcisigsq[2]*lciobs[i]/lcirate[i] lcmeen[2,i] <- lcmu[2] + lctheta2[i] lcirate[i] ~ dnorm( lcmeen[2,i], lcprecis[2,i]) lcprecis[3,i] <- lcisigsq[3]*lcscreen[i] lcmeen[3,i] <- lcmu[3] + lctheta3[i] lccursmkpct[i] ~ dnorm( lcmeen[3,i], lcprecis[3,i]) } for (i in 1:3) { lcmeana[i] <- mean( lcmeen[i,] ) lcstda[i] <- sd( lcmeen[i,] ) } for (i in 1:regions) { for (k in 1:3) { lcmean[k,i] <- (lcmeen[k,i] - lcmeana[k]) / lcstda[k] } } for (i in 1:regions) { plcetast[i] <- plcmortwt*lcmean[1,i] + plcincwt*lcmean[2,i] + plccursmkwt*lcmean[3,i] olcetast[i] <- olcmortwt*lcmean[1,i] + olcincwt*lcmean[2,i] + olccursmkwt*lcmean[3,i] } # lcStLouis <- rank( plcetast[],69 ) # lcHenn <- rank( plcetast[],27 ) # lcRock <- rank( plcetast[],67) # lcKoochiching <- rank( plcetast[],36 ) # lcStLouis1 <- rank( lcmean[1,],69 ) # lcHenn1 <- rank( lcmean[1,],27 ) # lcRock1 <- rank( lcmean[1,],67) # lcKoochiching1 <- rank( lcmean[1,],36 ) # lcStLouis2 <- rank( lcmean[2,],69 ) # lcHenn2 <- rank( lcmean[2,],27 ) # lcRock2 <- rank( lcmean[2,],67) # lcKoochiching2 <- rank( lcmean[2,],36 ) # lcStLouis3 <- rank( lcmean[3,],69 ) # lcHenn3 <- rank( lcmean[3,],27 ) # lcRock3 <- rank( lcmean[3,],67) # lcKoochiching3 <- rank( lcmean[3,],36 ) ########### standardize again, before coming up with etafinal: #### # pbcmean2 <- mean( pbcetast[] ) # pcrcmean2 <- mean( pcrcetast[] ) # plcmean2 <- mean( plcetast[] ) # pbcsd2 <- sd( pbcetast[] ) # pcrcsd2 <- sd( pcrcetast[] ) # plcsd2 <- sd( plcetast[] ) # obcmean2 <- mean( obcetast[] ) # ocrcmean2 <- mean( ocrcetast[] ) # olcmean2 <- mean( olcetast[] ) # obcsd2 <- sd( obcetast[] ) # ocrcsd2 <- sd( ocrcetast[] ) # olcsd2 <- sd( olcetast[] ) # for (i in 1:regions) { # pbcave2[i] <- (pbcetast[i] - pbcmean2) / pbcsd2 # pcrcave2[i] <- (pcrcetast[i] - pcrcmean2) / pcrcsd2 # plcave2[i] <- (plcetast[i] - plcmean2) / plcsd2 # obcave2[i] <- (obcetast[i] - obcmean2) / obcsd2 # ocrcave2[i] <- (ocrcetast[i] - ocrcmean2) / ocrcsd2 # olcave2[i] <- (olcetast[i] - olcmean2) / olcsd2 # } ########### end of 2nd standardization ############################### ##### (2nd standardization commented out b/c it didn't change anything...) ##### ####################################### ####### Combine the 3 cancer types ######## ####### Standardized & non-standardized #### ####################################### for (i in 1:regions) { petafinal[i] <- (pbcetast[i] + pcrcetast[i] + plcetast[i])/3 oetafinal[i] <- (obcetast[i] + ocrcetast[i] + olcetast[i])/3 # petafinal2[i] <- (pbcave2[i] + pcrcave2[i] + plcave2[i])/3 # oetafinal2[i] <- (obcave2[i] + ocrcave2[i] + olcave2[i])/3 } } ################ End of Model ################ # WInBUGS gamma convention: E = alpha/lambda, V = alpha/lambda^2 # bcmortalityrate = mortality / 100k # bcincidencerate = incidence / 100k # bcstagingpct = % diagnosed at late stage # bcmamnotpct = % who didn't get screened bcisigsq=c(.15,.01,.002,.003), =============================================================== ################################### # Initializations: chain 1: ################################### list( bcisigsq=c(.15,.01,.002,.003), crcisigsq=c(.01,.01,.01,.01), lcisigsq=c(.01,.01,.01), bclambda=c(1,1,1,1), bcmu=c(0,0,0,0), bctheta1=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), bctheta2=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), bctheta3=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), bctheta4=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0) , crclambda=c(1,1,1,1), crcmu=c(0,0,0,0), crctheta1=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), crctheta2=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), crctheta3=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), crctheta4=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0) , lclambda=c(1,1,1), lcmu=c(0,0,0), lctheta1=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), lctheta2=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0), lctheta3=c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0) ) #bcisigsq=c(.15,.01,.002,.003), crcisigsq=c(.01,.01,.01,.01), lcisigsq=c(.01,.01,.01), # This list is for checking convergence, e.g. via G-R statistic: ################################### # Initializations: chain 2: ################################### list( bcisigsq=c(.10,.001,.001,.001), crcisigsq=c(.005,.005,.005,.005), lcisigsq=c(.005,.005,.005), bclambda=c(66,44,11,55),bcmu=c(10,20,30,40), bctheta1=c(7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7), bctheta2=c(5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5), bctheta3=c(3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3), bctheta4=c(9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9), crclambda=c(66,44,11,55),crcmu=c(10,20,30,40), crctheta1=c( 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10,10,10), crctheta2=c(3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3,3), crctheta3=c(5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5,5, 5,5,5,5,5,5,5,5,5,5,5), crctheta4=c(7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7,7), lclambda=c(66,44,11),lcmu=c(10,20,30), lctheta1=c(2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2, 2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2, 2,2,2,2,2,2,2,2,2,2,2), lctheta2=c(4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4), lctheta3=c(6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6, 6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6, 6,6,6,6,6,6,6,6,6,6,6) ) #bcisigsq=c(.15,.01,.002,.003), crcisigsq=c(.01,.01,.01,.01), lcisigsq=c(.01,.01,.01), ################################### # Initializations: chain 3: ################################### list( bcisigsq=c(.3,.1,.02,.03), crcisigsq=c(.05,.05,.05,.05), lcisigsq=c(.05,.05,.05), bclambda=c(55,66,44,11),bcmu=c(40,10,20,30), bctheta1=c(3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3), bctheta2=c(1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1), bctheta3=c(8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8), bctheta4=c(10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10,10,10,10, 10,10,10,10,10,10,10), crclambda=c(55,66,44,11),crcmu=c(40,10,20,30), crctheta1=c(8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8,8, 8,8,8,8,8,8,8,8,8,8,8), crctheta2=c(2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2, 2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2,2, 2,2,2,2,2,2,2,2,2,2,2), crctheta3=c(4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4,4, 4,4,4,4,4,4,4,4,4,4,4), crctheta4=c(3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3,3, 3,3,3,3,3,3,3,3,3,3,3), lclambda=c(55,66,44),lcmu=c(40,10,20), lctheta1=c(7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7,7, 7,7,7,7,7,7,7,7,7,7,7), lctheta2=c(6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6, 6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6,6, 6,6,6,6,6,6,6,6,6,6,6), lctheta3=c(9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9,9, 9,9,9,9,9,9,9,9,9,9,9) ) #=============================================================== # Use these numbers for "usual" rates: # Rates for mortality and incidence are cases /100k, # Screening and staging figures are expressed as percents, 0-100. bcincidencerate=c(128.2, 93.7, 108.3, 88.8, 88.5, 129.2, 105.3, 96.2, 104.1, 92, 129.3, 97.3, 103, 98.7, 114.1, 91.2, 111.4, 112.3, 119.2, 96.2, 96, 74.7, 85.9, 93.3, 110.2, 144.4, 122.9, 104.3, 111.1, 107.9, 115.3, 77.1, 81.3, 125.1, 81.6, 114.3, 82.7, 130.3, 118.6, 121.4, 73.4, 94.6, 120.6, 98.5, 107.9, 104, 90.1, 86.8, 95.7, 99.1, 84.6, 92.7, 95.8, 72.5, 129.7, 107.8, 131.5, 103.7, 128.7, 107.7, 90.2, 116.1, 65.4, 103.4, 89, 111.4, 116.4, 110.8, 105.9, 97.7, 127.6, 123.4, 110.1, 120.3, 85.8, 125.2, 78.2, 105.3, 106.6, 148, 110.5, 121.9, 95, 103.6, 110.4, 92.9, 85.4), bcmortalityrate=c(18.3, 21.7, 21.1, 18.5, 18.7, 29.4, 23.5, 17.5, 11, 14.7, 22.4, 21.6, 20.7, 20.9, 39.8, 14.6, 26.1, 28.6, 23.7, 25.1, 20.9, 26.1, 23.7, 25.1, 35.2, 36.3, 25.9, 26.3, 21.8, 28.6, 26.8, 31.3, 10.7, 28.3, 31.8, 21.5, 14.3, 22.7, 20.5, 31.6, 52.7, 27.1, 21.4, 32.8, 12, 27.1, 32.5, 26.6, 22, 22, 12.7, 17.1, 16.6, 20, 25.1, 21.4, 23.3, 19.4, 37.5, 17.7, 16.6, 22.9, 8.1, 22.2, 20.3, 26.2, 29.2, 24.5, 21.6, 27.5, 25.1, 42.8, 21.3, 23.3, 26.5, 24.1, 16.9, 37.2, 19.1, 31, 21.8, 22.6, 27.6, 20.6, 15.5, 22.1, 20.3), bcmamnotpct = c( 21.74,8.66,30.30,27.27,18.75,25.00,13.46,18.18,14.29,16.67,17.86,0.00, 30.00,11.36,0.00,0.00,15.79,18.75,9.66,14.29,20.59,19.05,11.54,16.67, 21.74,14.29,12.76,15.79,22.22,20.00,17.54,20.00,21.05,28.57,40.00,0.00, 42.86,8.33,50.00,21.43,12.50,34.78,20.00,20.00,25.00,24.00,12.00,22.73, 23.08,12.82,16.67,0.00,28.00,16.67,16.33,20.75,0.00,16.67,14.29,24.39, 20.00,12.91,0.00,17.24,14.29,5.56,21.05,15.38,14.68,16.67,9.09,30.77, 18.60,21.43,27.27,33.33,36.36,0.00,18.18,16.00,7.14,15.65,0.00,50.00, 9.30,16.67,20.00), bcstagingpct=c(31.82, 26.89, 35.21, 29.51, 32.08, 7.69, 26.23, 32.26, 19.23, 29.47, 34.62, 21.62, 29.55, 27.27, 42.11, 25, 25.64, 27.74, 27.07, 38.71, 28.79, 29.27, 23.91, 25.32, 33.03, 19.23, 26.26, 22.73, 22.45, 37.7, 20.51, 52.63, 13.04, 26.32, 20, 25, 30.77, 34.21, 37.5, 29.09, 18.18, 18.52, 30.21, 54.55, 36.67, 27.4, 38.46, 42.55, 30, 22.55, 19.23, 30, 22.22, 37.5, 25.25, 20, 33.33, 30, 17.95, 32.97, 21.88, 26.2, 25, 23.91, 25, 34.43, 20.51, 54.17, 27.03, 20.88, 30.34, 36, 26.75, 37.8, 17.65, 41.94, 27.5, 31.25, 22.22, 31.11, 33.33, 27.78, 26.67, 42.11, 33.63, 27.56, 24.24), # Use these numbers for emphasizing incidence: # Per million for incidence (i.e. multiply above figures by 10) # Per thousand for mortality (i.e. divide above figures by 100) # Staging and screening as fractions between 0 and 1 (i.e. divide above figures by 100) bcincidencerate=c( 1282,937,1083,888,885,1292,1053,962,1041,920,1293,973, 1030,987,1141,912,1114,1123,1192,962,960,747,859,933, 1102,1444,1229,1043,1111,1079,1153,771,813,1251,816,1143, 827,1303,1186,1214,734,946,1206,985,1079,1040,901,868, 957,991,846,927,958,725,1297,1078,1315,1037,1287,1077, 902,1161,654,1034,890,1114,1164,1108,1059,977,1276,1234, 1101,1203,858,1252,782,1053,1066,1480,1105,1219,950,1036, 1104,929,854), bcmortalityrate=c( 0.183,0.217,0.211,0.185,0.187,0.294,0.235,0.175,0.11,0.147,0.224,0.216, 0.207,0.209,0.398,0.146,0.261,0.286,0.237,0.251,0.209,0.261,0.237,0.251, 0.352,0.363,0.259,0.263,0.218,0.286,0.268,0.313,0.107,0.283,0.318,0.215, 0.143,0.227,0.205,0.316,0.527,0.271,0.214,0.328,0.12,0.271,0.325,0.266, 0.22,0.22,0.127,0.171,0.166,0.2,0.251,0.214,0.233,0.194,0.375,0.177, 0.166,0.229,0.081,0.222,0.203,0.262,0.292,0.245,0.216,0.275,0.251,0.428, 0.213,0.233,0.265,0.241,0.169,0.372,0.191,0.31,0.218,0.226,0.276,0.206, 0.155,0.221,0.203), bcmamnotpct=c( 0.2174,0.08661,0.303,0.2727,0.1875,0.25,0.1346,0.1818,0.1429,0.1667,0.1786,0, 0.3,0.1136,0,0,0.1579,0.1875,0.09659,0.1429,0.2059,0.1905,0.1154,0.1667, 0.2174,0.1429,0.1276,0.1579,0.2222,0.2,0.1754,0.2,0.2105,0.2857,0.4,0, 0.4286,0.08333,0.5,0.2143,0.125,0.3478,0.2,0.2,0.25,0.24,0.12,0.2273, 0.2308,0.1282,0.1667,0,0.28,0.1667,0.1633,0.2075,0,0.1667,0.1429,0.2439, 0.2,0.1291,0,0.1724,0.1429,0.05556,0.2105,0.1538,0.1468,0.1667,0.09091,0.3077, 0.186,0.2143,0.2727,0.3333,0.3636,0,0.1818,0.16,0.07143,0.1565,0,0.5, 0.09302,0.1667,0.2), bcstagingpct=c( 0.3182,0.2689,0.3521,0.2951,0.3208,0.0769,0.2623,0.3226,0.1923,0.2947,0.3462,0.2162, 0.2955,0.2727,0.4211,0.25,0.2564,0.2774,0.2707,0.3871,0.2879,0.2927,0.2391,0.2532, 0.3303,0.1923,0.2626,0.2273,0.2245,0.377,0.2051,0.5263,0.1304,0.2632,0.2,0.25, 0.3077,0.3421,0.375,0.2909,0.1818,0.1852,0.3021,0.5455,0.3667,0.274,0.3846,0.4255, 0.3,0.2255,0.1923,0.3,0.2222,0.375,0.2525,0.2,0.3333,0.3,0.1795,0.3297, 0.2188,0.262,0.25,0.2391,0.25,0.3443,0.2051,0.5417,0.2703,0.2088,0.3034,0.36, 0.2675,0.378,0.1765,0.4194,0.275,0.3125,0.2222,0.3111,0.3333,0.2778,0.2667,0.4211, 0.3363,0.2756,0.2424), # prevention weights: pbcscreenwt=.4, pbcstagingwt=.3, pbcmortwt=.2, pbcincwt=.1, pcrcscreenwt=.4,pcrcstagingwt=.3, pcrcmortwt=.2, pcrcincwt=.1, plccursmkwt=.7, plcmortwt=.15, plcincwt=.15, # outcome weights: obcscreenwt=.1, obcstagingwt=.3, obcmortwt=.4, obcincwt=.2, ocrcscreenwt=.1,ocrcstagingwt=.3, ocrcmortwt=.4, ocrcincwt=.2, olccursmkwt=.1, olcmortwt=.5, olcincwt=.4, ilama=.01, ilamb=.01, ilama=1.0, ilamb=1.0, ilama=10,ilamb=0.5 ilama=4, ilamb=0.2 # seed 93845 #=============================================================== # Recall for WInBUGS, Gamma(alpha,beta) has mean alpha/beta and var alpha/beta^2 ###################### #### Data : ##### ###################### list(regions=87, isiga=.01, isigb=.01, ilama=4, ilamb=.2, pbcscreenwt=.4, pbcstagingwt=.3, pbcmortwt=.2, pbcincwt=.1, pcrcscreenwt=.4,pcrcstagingwt=.3, pcrcmortwt=.1, pcrcincwt=.2, plccursmkwt=.7, plcmortwt=.15, plcincwt=.15, obcscreenwt=.1, obcstagingwt=.3, obcmortwt=.4, obcincwt=.2, ocrcscreenwt=.1,ocrcstagingwt=.3, ocrcmortwt=.4, ocrcincwt=.2, olccursmkwt=.1, olcmortwt=.5, olcincwt=.4, bcincidencerate=c(128.2, 93.7, 108.3, 88.8, 88.5, 129.2, 105.3, 96.2, 104.1, 92, 129.3, 97.3, 103, 98.7, 114.1, 91.2, 111.4, 112.3, 119.2, 96.2, 96, 74.7, 85.9, 93.3, 110.2, 144.4, 122.9, 104.3, 111.1, 107.9, 115.3, 77.1, 81.3, 125.1, 81.6, 114.3, 82.7, 130.3, 118.6, 121.4, 73.4, 94.6, 120.6, 98.5, 107.9, 104, 90.1, 86.8, 95.7, 99.1, 84.6, 92.7, 95.8, 72.5, 129.7, 107.8, 131.5, 103.7, 128.7, 107.7, 90.2, 116.1, 65.4, 103.4, 89, 111.4, 116.4, 110.8, 105.9, 97.7, 127.6, 123.4, 110.1, 120.3, 85.8, 125.2, 78.2, 105.3, 106.6, 148, 110.5, 121.9, 95, 103.6, 110.4, 92.9, 85.4), bcmortalityrate=c(18.3, 21.7, 21.1, 18.5, 18.7, 29.4, 23.5, 17.5, 11, 14.7, 22.4, 21.6, 20.7, 20.9, 39.8, 14.6, 26.1, 28.6, 23.7, 25.1, 20.9, 26.1, 23.7, 25.1, 35.2, 36.3, 25.9, 26.3, 21.8, 28.6, 26.8, 31.3, 10.7, 28.3, 31.8, 21.5, 14.3, 22.7, 20.5, 31.6, 52.7, 27.1, 21.4, 32.8, 12, 27.1, 32.5, 26.6, 22, 22, 12.7, 17.1, 16.6, 20, 25.1, 21.4, 23.3, 19.4, 37.5, 17.7, 16.6, 22.9, 8.1, 22.2, 20.3, 26.2, 29.2, 24.5, 21.6, 27.5, 25.1, 42.8, 21.3, 23.3, 26.5, 24.1, 16.9, 37.2, 19.1, 31, 21.8, 22.6, 27.6, 20.6, 15.5, 22.1, 20.3), bcmamnotpct = c( 21.74,8.66,30.30,27.27,18.75,25.00,13.46,18.18,14.29,16.67,17.86,0.00, 30.00,11.36,0.00,0.00,15.79,18.75,9.66,14.29,20.59,19.05,11.54,16.67, 21.74,14.29,12.76,15.79,22.22,20.00,17.54,20.00,21.05,28.57,40.00,0.00, 42.86,8.33,50.00,21.43,12.50,34.78,20.00,20.00,25.00,24.00,12.00,22.73, 23.08,12.82,16.67,0.00,28.00,16.67,16.33,20.75,0.00,16.67,14.29,24.39, 20.00,12.91,0.00,17.24,14.29,5.56,21.05,15.38,14.68,16.67,9.09,30.77, 18.60,21.43,27.27,33.33,36.36,0.00,18.18,16.00,7.14,15.65,0.00,50.00, 9.30,16.67,20.00), bcstagingpct=c(31.82, 26.89, 35.21, 29.51, 32.08, 7.69, 26.23, 32.26, 19.23, 29.47, 34.62, 21.62, 29.55, 27.27, 42.11, 25, 25.64, 27.74, 27.07, 38.71, 28.79, 29.27, 23.91, 25.32, 33.03, 19.23, 26.26, 22.73, 22.45, 37.7, 20.51, 52.63, 13.04, 26.32, 20, 25, 30.77, 34.21, 37.5, 29.09, 18.18, 18.52, 30.21, 54.55, 36.67, 27.4, 38.46, 42.55, 30, 22.55, 19.23, 30, 22.22, 37.5, 25.25, 20, 33.33, 30, 17.95, 32.97, 21.88, 26.2, 25, 23.91, 25, 34.43, 20.51, 54.17, 27.03, 20.88, 30.34, 36, 26.75, 37.8, 17.65, 41.94, 27.5, 31.25, 22.22, 31.11, 33.33, 27.78, 26.67, 42.11, 33.63, 27.56, 24.24), bcdeaths=c(14, 134, 24, 19, 19, 8, 41, 23, 13, 26, 19, 13, 24, 37, 13, 4, 17, 55, 169, 13, 25, 22, 20, 35, 57, 11, 875, 21, 15, 22, 44, 16, 6, 41, 7, 15, 8, 11, 5, 30, 14, 25, 27, 6, 6, 22, 24, 24, 22, 42, 10, 16, 19, 10, 83, 50, 14, 16, 15, 30, 7, 390, 2, 16, 15, 41, 15, 10, 184, 43, 30, 22, 73, 25, 8, 9, 17, 8, 18, 15, 16, 93, 16, 5, 34, 44, 14), bcincidence=c(70, 597, 102, 92, 74, 33, 162, 99, 107, 136, 116, 56, 108, 156, 31, 16, 62, 198, 850, 47, 111, 57, 71, 118, 152, 37, 3846, 71, 66, 82, 172, 33, 37, 169, 22, 60, 36, 55, 19, 96, 24, 78, 125, 15, 43, 95, 68, 63, 102, 156, 36, 70, 79, 25, 399, 232, 59, 75, 53, 128, 46, 1737, 11, 70, 62, 159, 54, 47, 784, 154, 138, 63, 354, 122, 31, 51, 67, 22, 70, 72, 73, 498, 43, 29, 167, 181, 44), bcstagingtot=c(44, 450, 71, 61, 53, 26, 122, 62, 78, 95, 78, 37, 88, 99, 19, 8, 39, 137, 628, 31, 66, 41, 46, 79, 109, 26, 2749, 44, 49, 61, 117, 19, 23, 114, 15, 40, 26, 38, 8, 55, 11, 54, 96, 11, 30, 73, 52, 47, 60, 102, 26, 50, 54, 16, 301, 165, 42, 50, 39, 91, 32, 1252, 8, 46, 48, 122, 39, 24, 529, 91, 89, 50, 243, 82, 17, 31, 40, 16, 45, 45, 48, 360, 30, 19, 113, 127, 33), bcmamtot=c(23, 127, 33, 22, 32, 12, 52, 22, 21, 24, 28, 17, 20, 44, 8, 5, 19, 48, 176, 14, 34, 21, 26, 42, 46, 7, 807, 19, 18, 15, 57, 10, 19, 42, 10, 9, 7, 12, 2, 28, 8, 23, 25, 5, 8, 25, 25, 22, 39, 39, 6, 16, 25, 12, 98, 53, 17, 18, 14, 41, 15, 426, 2, 29, 14, 36, 19, 13, 218, 36, 22, 13, 86, 28, 11, 9, 11, 1, 11, 25, 14, 115, 7, 2, 43, 54, 5), crcdrate=c(22.4, 12.3, 19.3, 20.9, 13.4, 24.1, 14.4, 18.7, 14.4, 20.6, 12.9, 15.3, 16.7, 14.0, 13.2, 6.4, 13.6, 15.4, 14.5, 11.9, 16.1, 17.4, 17.5, 14.7, 15.8, 21.4, 14.3, 14.0, 15.6, 9.9, 21.7, 13.7, 21.6, 15.0, 9.2, 11.7, 16.7, 15.7, 3.0, 13.7, 35.1, 10.9, 14.2, 19.6, 14.1, 19.6, 12.7, 16.8, 15.6, 20.7, 9.9, 13.0, 12.8, 25.8, 14.1, 16.6, 15.0, 17.5, 18.9, 19.7, 17.3, 15.5, 13.2, 20.6, 13.0, 17.7, 13.8, 12.7, 15.1, 17.3, 19.1, 25.8, 12.9, 18.7, 20.2, 19.5, 13.3, 16.4, 15.8, 22.3, 10.8, 17.3, 21.0, 21.6, 19.0, 13.5, 26.2), crcirate=c(50.5, 36.5, 46.7, 45.3, 52.8, 64.6, 46.9, 47.7, 43.4, 46.3, 45.2, 40.3, 54.2, 42.9, 52.6, 32.4, 51.3, 34.8, 45.1, 44.8, 44.0, 40.9, 41.3, 40.1, 36.3, 67.4, 40.4, 50.6, 44.6, 32.7, 55.5, 37.7, 37.4, 38.1, 45.3, 35.1, 43.8, 43.7, 34.8, 38.9, 56.8, 44.3, 41.5, 50.0, 53.5, 51.7, 43.4, 42.2, 46.9, 67.0, 39.3, 38.9, 39.7, 46.2, 44.8, 49.6, 50.0, 48.9, 36.1, 49.9, 47.6, 39.2, 38.4, 47.6, 39.1, 39.4, 30.7, 41.7, 45.1, 41.6, 54.8, 53.2, 38.3, 38.5, 56.6, 67.3, 36.3, 53.8, 47.4, 52.5, 39.7, 43.1, 61.8, 63.7, 48.1, 42.9, 60.9), crcstagingpct=c(45.24, 52.98, 33.33, 71.93, 56.86, 57.69, 59.38, 57.38, 51.43, 58.90, 55.88, 78.79, 52.46, 47.01, 63.64, 70.00, 52.38, 58.14, 56.64, 66.67, 61.76, 78.26, 57.45, 56.92, 65.22, 59.09, 60.62, 40.48, 39.53, 52.94, 47.66, 50.00, 60.00, 61.11, 75.00, 64.52, 68.42, 46.15, 81.82, 50.00, 58.62, 63.64, 63.16, 55.56, 65.71, 66.15, 56.00, 50.00, 54.79, 47.65, 73.68, 57.58, 52.17, 61.90, 64.63, 51.23, 44.74, 51.02, 60.00, 66.22, 51.22, 57.14, 50.00, 75.00, 73.68, 60.26, 72.22, 54.55, 52.06, 55.84, 70.42, 50.00, 52.98, 50.85, 59.26, 64.10, 51.16, 40.00, 72.22, 62.22, 50.00, 51.79, 68.29, 58.33, 62.77, 58.33, 42.22), crcnotscreenpct = c( 76.67,55.25,73.17,65.38,44.83,61.54,69.64,54.17,69.57,60.00, 72.00,61.11,56.52,47.17,50.00,33.33,76.92,63.24,47.85,66.67, 69.44,50.00,57.58,78.00,66.67,83.33,54.29,65.22,83.33,60.00, 60.94,55.56,77.27,59.57,100.00,80.00,80.00,50.00,100.00,67.74, 57.14,56.00,69.44,66.67,41.67,63.64,50.00,70.00,62.79,54.55, 66.67,57.89,76.92,66.67,53.27,72.73,78.57,56.52,91.67,75.00, 90.00,54.45,100.00,69.23,64.71,63.41,60.00,75.00,69.01,52.08, 62.50,66.67,60.00,70.27,50.00,90.00,68.42,100.00,71.43,68.75, 63.64,55.81,62.50,100.00,65.52,67.44,100.00), crcdobs=c(27, 131, 41, 46, 27, 17, 53, 42, 32, 52, 29, 22, 34, 48, 11, 2, 19, 62, 176, 11, 41, 32, 31, 43, 52, 16, 915, 26, 22, 18, 72, 17, 19, 42, 9, 15, 19, 17, 1, 28, 27, 22, 35, 10, 15, 39, 25, 29, 30, 83, 13, 22, 22, 19, 91, 82, 17, 31, 19, 51, 18, 494, 4, 37, 25, 54, 10, 17, 249, 46, 41, 27, 94, 41, 18, 21, 27, 9, 27, 30, 16, 113, 18, 13, 64, 54, 30), crciobs=c(62, 391, 97, 96, 87, 39, 152, 98, 96, 117, 92, 51, 111, 138, 35, 11, 66, 130, 538, 42, 103, 73, 75, 102, 104, 41, 2373, 70, 59, 48, 178, 42, 36, 99, 23, 45, 36, 41, 10, 68, 41, 85, 91, 22, 48, 94, 72, 69, 100, 235, 35, 57, 67, 35, 281, 231, 50, 79, 35, 122, 49, 1138, 15, 75, 61, 112, 26, 45, 695, 112, 108, 61, 262, 84, 43, 58, 64, 22, 66, 67, 57, 287, 56, 35, 153, 157, 62), crcstagn =c(42, 285, 72, 57, 51, 26, 96, 61, 70, 73, 68, 33, 61, 117, 22, 10, 42, 86, 369, 24, 68, 46, 47, 65, 69, 22, 1488, 42, 43, 34, 107, 22, 20, 72, 16, 31, 19, 26, 11, 46, 29, 44, 57, 18, 35, 65, 50, 46, 73, 149, 19, 33, 46, 21, 164, 162, 38, 49, 15, 74, 41, 749, 12, 52, 38, 78, 18, 33, 461, 77, 71, 38, 168, 59, 27, 39, 43, 15, 36, 45, 32, 168, 41, 24, 94, 108, 45), crcscreen=c(30, 181, 41, 26, 29, 13, 56, 24, 23, 30, 25, 18, 23, 53, 8, 6, 13, 68, 186, 9, 36, 18, 33, 50, 45, 6, 991, 23, 18, 25, 64, 9, 22, 47, 12, 10, 15, 8, 1, 31, 7, 25, 36, 6, 12, 33, 38, 20, 43, 44, 3, 19, 26, 12, 107, 55, 14, 23, 12, 40, 10, 494, 5, 26, 17, 41, 20, 20, 242, 48, 32, 12, 85, 37, 12, 10, 19, 3, 14, 32, 11, 129, 8, 3, 58, 43, 2), lcdrate = c( 49.85,44.14,47.11,44.32,50.17,40.31,30.91,34.14,44.80,34.04,43.78,32.46, 53.33,31.02,41.65,21.03,32.92,35.27,41.12,31.03,36.73,25.94,33.88,37.35, 32.75,24.84,42.72,41.60,55.75,40.30,51.48,31.05,42.89,30.87,56.37,46.77, 37.73,55.03,48.86,29.51,42.86,36.00,20.80,38.83,23.11,27.25,28.52,46.42, 35.63,39.14,24.78,33.60,31.41,44.54,32.21,33.81,26.57,57.54,35.70,48.40, 45.97,44.66,29.54,32.92,29.70,40.29,36.97,40.63,44.61,38.63,45.26,33.28, 35.78,31.40,29.77,43.56,46.02,35.71,38.93,32.99,34.58,42.12,52.43,26.91, 39.32,38.81,42.83), lcirate = c( 56.26,49.55,59.01,59.63,55.93,50.03,36.56,40.89,52.12,38.58,62.24,42.43, 60.89,39.31,46.62,47.26,44.08,51.96,49.04,41.72,49.89,40.16,36.93,44.90, 44.26,27.19,53.00,47.60,72.99,49.41,54.94,28.88,47.65,44.59,45.33,54.88, 41.32,58.40,40.33,38.48,36.70,47.81,32.58,66.64,40.12,40.41,25.66,75.87, 50.97,49.62,27.26,45.57,30.55,54.98,51.96,40.70,42.72,66.64,46.22,52.20, 43.76,51.11,36.28,39.49,35.95,49.48,37.15,37.85,53.49,37.87,47.23,40.88, 44.33,42.45,47.52,48.64,40.69,46.55,44.70,53.01,45.80,46.75,53.45,48.02, 47.49,49.29,41.53), lccursmkpct = c( 29.41,26.05,19.55,21.43,24.11,20.59,20.58,19.17,21.85,22.31,22.05,12.50, 26.95,16.67,23.68,22.86,16.92,23.62,22.02,23.94,13.46,23.16,13.39,22.38, 20.45,27.59,20.75,8.65,23.38,31.30,23.66,23.21,26.32,17.56,12.90,23.88, 33.33,25.45,21.05,20.00,21.05,14.71,21.76,9.09,25.00,12.31,21.95,24.72, 14.62,17.35,18.52,18.69,13.54,25.53,18.54,18.84,14.67,22.11,19.67,20.50, 19.05,22.60,21.43,20.00,20.24,27.24,19.67,24.42,25.40,23.84,27.27,16.90, 20.59,16.56,19.61,22.22,26.88,18.18,25.00,17.02,25.27,21.81,18.60,9.38, 19.74,23.50,17.95), lcdobs=c(60,447,93,86,80,21,94,69,88,77,86,38,97,95,30, 6,32,132,457,29,84,45,58,93,88,16,2366,57,73,57, 153,29,36,77,25,52,29,49,17,48,33,56,47,16,20, 57,44,64,74,123,22,43,49,30,181,144,25,88,30,114, 41,1223,10,43,51,106,35,37,625,93,84,34,225,58,19, 38,74,16,57,34,42,264,42,15,114,134,43), lciobs=c(68,519,110,112,82,23,103,77,98,85,118,40,108,111,26, 14,38,181,549,38,101,59,58,104,113,14,2830,61,90,64, 160,28,39,104,19,60,32,50,11,58,26,70,68,23,32, 72,38,98,99,146,22,57,45,32,285,166,41,96,35,116, 38,1331,11,50,51,126,31,30,714,91,86,39,266,78,29, 40,64,21,60,49,52,292,44,21,124,162,40), lcscreen=c(102,1236,179,182,141,34,311,120,119,260,127,56,141,246,38, 35,65,254,1635,71,156,95,112,143,176,29,6230,104,77,131, 224,56,57,205,31,67,57,55,19,120,19,102,170,22,64, 130,123,89,171,196,27,107,96,47,604,292,75,95,61,161, 42,2739,28,90,84,246,61,86,1051,323,242,71,573,151,51, 27,93,22,56,94,91,949,43,32,304,349,39), adj = c(11, 31, 69, 9, 58, 33, 48, 18, 27, 71, 30, 13, 82, 62, 14, 54, 44, 15, 29, 80, 56, 45, 68, 39, 36, 31, 11, 29, 15, 57, 73, 49, 48, 71, 78, 75, 76, 37, 22, 46, 83, 8, 52, 40, 81, 83, 17, 64, 65, 52, 7, 1, 69, 58, 27, 70, 72, 43, 86, 29, 4, 31, 1, 18, 49, 77, 80, 37, 76, 34, 65, 87, 82, 2, 30, 58, 54, 3, 56, 84, 60, 57, 4, 29, 3, 44, 38, 32, 51, 64, 8, 83, 11, 1, 48, 49, 25, 66, 70, 27, 62, 82, 50, 74, 25, 55, 61, 26, 56, 77, 46, 7, 81, 24, 50, 55, 85, 28, 22, 81, 74, 50, 79, 55, 20, 66, 19, 78, 84, 56, 21, 75, 19, 70, 10, 86, 2, 62, 23, 85, 15, 4, 11, 80, 3, 2, 71, 48, 33, 13, 4, 36, 69, 1, 11, 53, 17, 46, 48, 1, 58, 30, 12, 76, 61, 73, 47, 65, 68, 45, 39, 4, 31, 69, 6, 12, 87, 69, 16, 68, 4, 36, 81, 7, 52, 72, 70, 66, 87, 42, 59, 41, 87, 64, 51, 10, 72, 65, 47, 86, 54, 60, 15, 3, 35, 68, 4, 57, 60, 32, 83, 7, 22, 34, 73, 86, 43, 65, 5, 49, 18, 1, 33, 30, 71, 77, 11, 18, 48, 5, 73, 24, 20, 55, 23, 53, 59, 42, 64, 17, 7, 8, 65, 72, 40, 67, 51, 32, 60, 44, 3, 14, 79, 85, 23, 50, 20, 25, 84, 14, 3, 80, 77, 21, 26, 45, 4, 15, 63, 60, 13, 33, 1, 9, 41, 51, 67, 45, 57, 63, 15, 44, 54, 76, 75, 21, 73, 34, 27, 2, 82, 19, 60, 57, 17, 51, 42, 87, 65, 8, 43, 72, 52, 8, 64, 87, 12, 34, 47, 74, 81, 40, 70, 19, 25, 59, 53, 35, 39, 45, 4, 36, 31, 1, 9, 38, 66, 40, 72, 10, 27, 19, 86, 73, 5, 48, 30, 2, 65, 43, 10, 70, 40, 52, 86, 47, 34, 61, 77, 49, 5, 71, 24, 81, 66, 20, 6, 78, 26, 61, 76, 12, 6, 75, 61, 34, 21, 56, 80, 11, 49, 73, 84, 26, 75, 6, 85, 55, 25, 56, 3, 29, 11, 77, 24, 22, 7, 40, 66, 74, 19, 62, 2, 13, 46, 17, 8, 7, 14, 56, 26, 78, 28, 23, 55, 79, 47, 73, 71, 27, 10, 43, 37, 12, 65, 64, 42, 41 ), weights = c(1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1, 1,1,1,1,1,1,1,1,1,1 ), num = c(8,6,7,9,4,4,7,6,3,5,8,5,4,4,6,1,5,4,6,4,4,4,4,4,5,5, 6,2,5,5,5,3,4,6,2,4,3,2,3,6,3,4,5,4,5,4,5,7,6,4,5, 5,3,4,6,7,5,4,3,6,5,4,2,6,9,6,2,4,5,6,6,6,8,4,5,5,6, 4,3,5,6,4,4,4,4,6,6) ) ========================================================================= bcincidencerate=c( 0.1282,0.0937,0.1083,0.0888,0.0885,0.1292,0.1053,0.0962,0.1041,0.092,0.1293,0.0973, 0.103,0.0987,0.1141,0.0912,0.1114,0.1123,0.1192,0.0962,0.096,0.0747,0.0859,0.0933, 0.1102,0.1444,0.1229,0.1043,0.1111,0.1079,0.1153,0.0771,0.0813,0.1251,0.0816,0.1143, 0.0827,0.1303,0.1186,0.1214,0.0734,0.0946,0.1206,0.0985,0.1079,0.104,0.0901,0.0868, 0.0957,0.0991,0.0846,0.0927,0.0958,0.0725,0.1297,0.1078,0.1315,0.1037,0.1287,0.1077, 0.0902,0.1161,0.0654,0.1034,0.089,0.1114,0.1164,0.1108,0.1059,0.0977,0.1276,0.1234, 0.1101,0.1203,0.0858,0.1252,0.0782,0.1053,0.1066,0.148,0.1105,0.1219,0.095,0.1036, 0.1104,0.0929,0.0854), bcincidencerate=c( 128200,93700,108300,88800,88500,129200,105300,96200,104100,92000,129300,97300, 103000,98700,114100,91200,111400,112300,119200,96200,96000,74700,85900,93300, 110200,144400,122900,104300,111100,107900,115300,77100,81300,125100,81600,114300, 82700,130300,118600,121400,73400,94600,120600,98500,107900,104000,90100,86800, 95700,99100,84600,92700,95800,72500,129700,107800,131500,103700,128700,107700, 90200,116100,65400,103400,89000,111400,116400,110800,105900,97700,127600,123400, 110100,120300,85800,125200,78200,105300,106600,148000,110500,121900,95000,103600, 110400,92900,85400), bcmortalityrate=c( 0.0183,0.0217,0.0211,0.0185,0.0187,0.0294,0.0235,0.0175,0.0110,0.0147, 0.0224,0.0216,0.0207,0.0209,0.0398,0.0146,0.0261,0.0286,0.0237,0.0251, 0.0209,0.0261,0.0237,0.0251,0.0352,0.0363,0.0259,0.0263,0.0218,0.0286, 0.0268,0.0313,0.0107,0.0283,0.0318,0.0215,0.0143,0.0227,0.0205,0.0316, 0.0527,0.0271,0.0214,0.0328,0.0120,0.0271,0.0325,0.0266,0.0220,0.0220, 0.0127,0.0171,0.0166,0.0200,0.0251,0.0214,0.0233,0.0194,0.0375,0.0177, 0.0166,0.0229,0.0081,0.0222,0.0203,0.0262,0.0292,0.0245,0.0216,0.0275, 0.0251,0.0428,0.0213,0.0233,0.0265,0.0241,0.0169,0.0372,0.0191,0.0310, 0.0218,0.0226,0.0276,0.0206,0.0155,0.0221,0.0203),