School of Public Health

 

Department of Biostatistics


PubH 8445 Statistics for Human Genetics and Molecular Biology- Fall 2013


Course Description

The course will focus on different statistical methodologies for detection of genetic loci for complex traits, either qualitative or quantitative. We will discuss statistical modeling of familial aggregation and segregation studies, basic principles of population genetics, multipoint and model-free linkage analysis, family-based and population-based association testing, and Genome Wide Association analysis.

Time: Tuesday and Thursday 9:45-11:00
InstructorDr.Saonli Basu, Mayo A454-3. Ph: (612) 624-2135. Email: saonliATumn.edu
Office Hours:Monday 2:00-3:00 PM
Location: MoosT 1-435
For whom intended: This course is designed for graduate students.
Prerequisites: Prequisites are Stat 8101-2 or equivalent; PubH8432; or instructor's consent. Some experience with Splus or R is useful; some background in molecular biology desirable.
Evaluations: Course evaluation will be based on homework assignments (60%) and a final project (40%).
Course web site: PubH 8445

The recommended books are: